Myelin Basic Protein / MBP Antibody
Catalogue Number: ALS15984-ABG
| Manufacturer: | Abcepta |
| Molecular Weight: | 33117 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Myelin basic protein, MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein, MBP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Chicken |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | ICC, IHC-P, WB |
Description
Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Additional Text
Gene Name
MBP
Gene ID
4155
Molecular Weight
33117
Storage Note
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 12 months. Sensitive to light.
Uniprot ID
P02686
Short Description
Chicken Polyclonal Antibody
Purification
Affinity Purified
Antigen Type
Synthetic Peptide, KLH Conjugated
Antibody Clonality
Polyclonal
ALS15984 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations