CD44 Antibody (clone IM7, PE, Cy7)

Catalogue Number: ALS16696-ABG

Manufacturer:Abcepta
Molecular Weight:81538
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, He .
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rat
Clone: IM7
Isotype: IgG2b, kappa
Immunogen:
Application: FC, IHC-P

Description

Description: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Additional Text

Gene Name

CD44

Gene ID

960

Uniprot ID

P16070

Molecular Weight

81538

Concentration

0.2 mg/ml

Storage Note

Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer. Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.

Short Description

Rat Monoclonal Antibody

Purification

Affinity Purified

Antibody Clonality

Monoclonal