MMP2 Antibody
Catalogue Number: AM1844B-ABG
AM1844B Image
AM1844B Image
AM1844B Image
AM1844B Image
AM1844B Image
Confocal immunofluorescent analysis of MMP2 Antibody (Cat#AM1844b) with MCF-7 cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).
AM1844B Image
MMP2 western blot analysis in T47D cell line lysates (35µg/lane).This demonstrates the MMP2 antibody detected the MMP2 protein (arrow).
AM1844B Image
MMP2 Antibody (Cat. #AM1844b)immunohistochemistry analysis in formalin fixed and paraffin embedded human gastric carcinoma followed by peroxidase conjµgation of the secondary antibody and DAB staining.This data demonstrates the use of MMP2 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
AM1844B Image
MMP2 Antibody (Cat. #AM1844b)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjµgation of the secondary antibody and DAB staining.This data demonstrates the use of MMP2 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
| Manufacturer: | Abcepta |
| Molecular Weight: | 73882 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1, PEX, MMP2, CLG4A |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Mouse |
| Clone: | 6E3F8 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | IF, IHC-P, WB |
Description
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Additional Text
Gene ID
4313
Uniprot ID
P08253
Molecular Weight
73882
Antibody Clonality
Monoclonal
Accession Number
NP_001121363.1,,NP_004521.1
Gene Name
MMP2
Short Description
Mouse Monoclonal Antibody (Mab)
Preparation
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
AM1844B Datasheet
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