XRN1 Antibody
Catalogue Number: AM8692B-ABG
AM8692B Image
AM8692B Image
All lanes : Anti-XRN1 Antibody at 1:2000 dilution Lane 1: K562 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 194 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
| Manufacturer: | Abcepta |
| Molecular Weight: | 194107 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | 5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ul, 50 ul |
| Host name: | Mouse |
| Clone: | 1647CT723.27.62 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | WB |
Description
Description: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Additional Text
Uniprot ID
Q8IZH2
Gene ID
54464
Antigen Type
Recombinant Protein
Molecular Weight
194107
Antibody Clonality
Monoclonal
Gene Name
XRN1
Short Description
Purified Mouse Monoclonal Antibody (Mab)
AM8692B Datasheet
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