Catalogue Number: AN000330P-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Pancreatic poLypeptide prohormone;PH;Pancreatic poLypeptide Y;Pancreatic poLypeptide;Pancreatic icosapeptide;PPY;PNP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 25 ug |
| Host name: | Rat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Human Pancreatic polypeptide/PPY protein expressed by E.coli |
| Application: | ELISA |
Description: Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying.
5539
P01298
Ppy
Affinity Purified
Polyclonal
1 mg/ml
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.