IgG Monoclonal Antibody(Capture)

Catalogue Number: AN001560P-ELA

Manufacturer:Elabscience
Preservative:0.05% ProClin™ 300
Type:Monoclonal Secondary Antibody - Unconjugated
Alias:IgG;ImmunogLobuLin G;ImmunogLobuLinG
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 25 ug
Host name: Mouse
Clone: 1H3
Isotype: IgG2b
Immunogen: Rabbit IgG Native Protein
Application: ELISA

Description

Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Additional Text

Antibody Clonality

Monoclonal

Concentration

1 mg/ml

Purification

Protein A/G Purification

Storage Note

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Price
£1,410.00


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