Elab Fluor® 488-conjugated Vinculin Monoclonal Antibody

Catalogue Number: AN00297L-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.02% Sodium azide
Type:Monoclonal Primary Antibody - Conjugated
Alias:Vinculin;Metavinculin (MV);VCL
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: 4D4
Isotype: IgG1
Immunogen: Recombinant Human Vinculin protein expressed by E.coli
Application: IF

Description

Description: Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa,1,066-amino-acid protein which is ubiquitously expressed. Its splice variant,metavinculin (124 kDa),is muscle-specific.

Additional Text

Gene Name

VCL

Uniprot ID

P18206

Gene ID

7414

Antibody Clonality

Monoclonal

Concentration

1 mg/ml

Purification

Protein A/G Purification

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.