PE/Elab Fluor® 594 Anti-Human CD46 Antibody[TRA-2-10]
Catalogue Number: AN00324P-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Complementmembranecofactorprotein;measlesvirusreceptor;MCP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 2 x 100 tests, 20 tests |
| Host name: | Mouse |
| Clone: | TRA-2-10 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.
Additional Text
Gene Name
CD46
Gene ID
4179
Concentration
5 ul/test
Uniprot ID
P15529
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
AN00324P MSDS
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