Nephrin (Y1210) antibody
Catalogue Number: AP10417A-ABG
AP10417a Image
AP10417a Image
AP10417a Image
AP10417a Image
AP10417a Image
Nephrin (Y1210) antibody (Cat. #AP10417a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).
AP10417a Image
Nephrin (Y1210) antibody (Cat. #AP10417a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).
AP10417a Image
All lanes : Anti-Nephrin (Y1210) antibody at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: A-498 whole cell lysate Lane 3: Caki-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 135 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
AP10417a Image
Nephrin Antibody (Y1210) (Cat. #AP10417a) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
| Manufacturer: | Abcepta |
| Molecular Weight: | 134742 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Rabbit |
| Clone: | RB28264 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | FC, WB |
Description
Description: This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Additional Text
Gene Name
NPHS1
Uniprot ID
O60500
Gene ID
4868
Accession Number
NP_004637.1
Antigen Type
Synthetic Peptide
Molecular Weight
134742
Antibody Clonality
Polyclonal
Short Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Preparation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
AP10417a Datasheet
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