LRP5 Antibody (C-term)
Catalogue Number: AP14655B-ABG
| Manufacturer: | Abcepta |
| Molecular Weight: | 179145 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Rabbit |
| Clone: | RB32191 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | WB |
Description
Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Additional Text
Antigen Type
Synthetic Peptide
Molecular Weight
179145
Accession Number
NP_002326.2
Antibody Clonality
Polyclonal
Uniprot ID
O75197, Q91VN0
Short Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Preparation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Gene ID
16973; 4041
Gene Name
Lrp5, LRP5
AP14655b Datasheet
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