Phospho-FRAP1(S2481) Antibody
Catalogue Number: AP3487A-ABG
| Manufacturer: | Abcepta |
| Molecular Weight: | 288892 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Rabbit |
| Clone: | RB13343 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | DB |
Description
Description: FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Additional Text
Antigen Type
Synthetic Peptide
Molecular Weight
288892
Specificity
Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Accession Number
NP_004949.1
Uniprot ID
P42345, P42346, Q9JLN9
Antibody Clonality
Polyclonal
Short Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Preparation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Gene ID
2475; 56717; 56718
Gene Name
Mtor, MTOR
AP3487A Datasheet
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