Phospho-RASGRF1(S929) Antibody
Catalogue Number: AP3496A-ABG
AP3496A Image
AP3496A Image
AP3496A Image
Western blot analysis of lysates from A431 cell line, untreated or treated with Forskolin(50µM, 30min), using Phospho-RASGRF1(S929) Antibody(upper) or Tubulin (lower).
AP3496A Image
Dot blot analysis of anti-RASGRF1-pS929 Pab (RB14017) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
| Manufacturer: | Abcepta |
| Molecular Weight: | 145234 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25, RASGRF1, CDC25, GNRP, GRF1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Rabbit |
| Clone: | RB14017 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | WB, DB |
Description
Description: RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
Additional Text
Gene ID
5923
Uniprot ID
Q13972
Antigen Type
Synthetic Peptide
Molecular Weight
145234
Accession Number
NP_722522.1
Antibody Clonality
Polyclonal
Gene Name
RASGRF1
Short Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Preparation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
AP3496A Datasheet
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