Phospho-MAPK14(T180) Antibody
Catalogue Number: AP3642A-ABG
AP3642A Image
AP3642A Image
AP3642A Image
Western blot analysis of lysates from 293 cell line, untreated or treated with UV(2h), using Phospho-MAPK14(T180) Antibody(upper) or Tubulin (lower).
AP3642A Image
Dot blot analysis of anti-Phospho-p38 MAPK-T180 Antibody (Cat.# AP3642a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
| Manufacturer: | Abcepta |
| Molecular Weight: | 41293 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 400 ul, 80 ul |
| Host name: | Rabbit |
| Clone: | RB15973 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | WB, DB |
Description
Description: MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Additional Text
Antigen Type
Synthetic Peptide
Molecular Weight
41293
Specificity
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a, MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
Antibody Clonality
Polyclonal
Accession Number
NP_001306.1,,NP_620581.1,,NP_620582.1,,NP_620583.1
Uniprot ID
P47811, P70618, Q16539, Q9DGE2
Short Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Preparation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Gene ID
1432; 26416; 65237
Gene Name
Mapk14, MAPK14, mapk14a
AP3642A Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations