CREBL1 Antibody (C-term)

Catalogue Number: AP5101B-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 400 ul, 80 ul
Host name: Rabbit
Clone: RB25603
Isotype: IgG
Immunogen:
Application: IHC-P, WB

Description

Description: CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Additional Text

Gene Name

ATF6B

Uniprot ID

Q99941

Gene ID

1388

Antigen Type

Synthetic Peptide

Molecular Weight

76709

Specificity

Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, Creb-rp, cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13

Antibody Clonality

Polyclonal

Accession Number

NP_001129625.1,,NP_004372.3

Short Description

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Preparation

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.