HMGA2 Antibody (C-term)

Catalogue Number: AP5359B-ABG

Manufacturer:Abcepta
Type:Polyclonal Primary Antibody - Unconjugated
Alias:High mobility group protein HMGI-C, High mobility group AT-hook protein 2, Hmga2, Hmgic
Shipping Condition:Blue Ice
Unit(s): 400 ul, 80 ul
Host name: Rabbit
Clone: RB21014
Isotype: IgG
Immunogen:
Application: FC, WB

Description

Description: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Additional Text

Gene ID

8091

Gene Name

Hmga2

Antigen Type

Synthetic Peptide

Molecular Weight

11832

Antibody Clonality

Polyclonal

Accession Number

NP_003474.1,,NP_003475.1

Uniprot ID

P52926, P52927

Short Description

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Preparation

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.