Transthyretin Antibody
Catalogue Number: ASC10901-ABG
ASC10901 Image
ASC10901 Image
ASC10901 Image
ASC10901 Image
Western blot analysis of Transthyretin in HepG2 cell lysate with Transthyretin antibody at (A) 1 and (B) 2 µg/mL.
ASC10901 Image
Immunohistochemistry of Transthyretin in human lung tissue with Transthyretin antibody at 2.5 µg/mL.
ASC10901 Image
Immunofluorescence of Transthyretin in human lung tissue with Transthyretin antibody at 20 µg/mL.
| Manufacturer: | Abcepta |
| Shelf Life: | 12 months |
| Molecular Weight: | 15887 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | |
| Application: | ELISA, IF, IHC-P, WB, IHC |
Description
Description: Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.
Additional Text
Gene Name
TTR
Uniprot ID
P02766
Gene ID
7276
Molecular Weight
15887
Application Notes
Transthyretin antibody can be used for detection of Transthyretin by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Storage Note
Transthyretin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ASC10901 Datasheet
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