AP2M1 Antibody
Catalogue Number: ASC10903-ABG
ASC10903 Image
ASC10903 Image
ASC10903 Image
ASC10903 Image
Western blot analysis of AP2M1 in human kidney tissue lysate with AP2M1 antibody at (A) 1 and (B) 2 µg/mL.
ASC10903 Image
Immunohistochemistry of AP2M1 in mouse kidney tissue with AP2M1 antibody at 2.5 µg/mL.
ASC10903 Image
Immunofluorescence of AP2M1 in Mouse Kidney cells with AP2M1 antibody at 20 µg/mL.
| Manufacturer: | Abcepta |
| Shelf Life: | 12 months |
| Molecular Weight: | 49655 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | |
| Application: | ELISA, IF, IHC-P, WB, IHC |
Description
Description: AP2M1 Antibody: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Additional Text
Gene Name
AP2M1
Uniprot ID
Q96CW1
Gene ID
1173
Molecular Weight
49655
Application Notes
AP2M1 antibody can be used for detection of AP2M1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Purification
Affinity Purified
Accession Number
NP_004059
Antibody Clonality
Polyclonal
Storage Note
AP2M1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ASC10903 Datasheet
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