TCC52 Antibody

Catalogue Number: ASC11110-ABG

Manufacturer:Abcepta
Shelf Life:12 months
Molecular Weight:50517
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Chicken
Clone:
Isotype: IgY
Immunogen:
Application: ELISA, ICC, WB

Description

Description: TCC52 Antibody: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.

Additional Text

Gene ID

25853

Gene Name

DCAF12

Uniprot ID

Q5T6F0

Molecular Weight

50517

Application Notes

TCC52 antibody can be used for detection of TCC52 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL.

Purification

Affinity Purified

Accession Number

NP_056212

Antibody Clonality

Polyclonal

Storage Note

TCC52 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.