SIRT4 Antibody
Catalogue Number: ASC11137-ABG
| Manufacturer: | Abcepta |
| Shelf Life: | 12 months |
| Molecular Weight: | 35188 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | |
| Application: | ELISA, WB |
Description
Description: SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.
Additional Text
Uniprot ID
Q9Y6E7
Gene ID
23409
Molecular Weight
35188
Application Notes
SIRT4 antibody can be used for detection of SIRT4 by Western blot at 1 - 2 µg/mL.
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Accession Number
EAW98182
Gene Name
SIRT4
Storage Note
SIRT4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ASC11137 Datasheet
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