SIRT5 Antibody

Catalogue Number: ASC11138-ABG

Manufacturer:Abcepta
Shelf Life:12 months
Molecular Weight:33881
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Chicken
Clone:
Isotype: IgY
Immunogen:
Application: ELISA, WB

Description

Description: SIRT5 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.

Additional Text

Uniprot ID

Q9NXA8

Accession Number

NP_036373

Gene ID

23408

Molecular Weight

33881

Application Notes

SIRT5 antibody can be used for detection of SIRT5 by Western blot at 1 - 2 µg/mL.

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Gene Name

SIRT5

Storage Note

SIRT5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.