SIRT7 Antibody
Catalogue Number: ASC11140-ABG
| Manufacturer: | Abcepta |
| Shelf Life: | 12 months |
| Molecular Weight: | 44898 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | |
| Application: | ELISA, WB |
Description
Description: SIRT7 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
Additional Text
Gene Name
SIRT7
Uniprot ID
Q9NRC8
Gene ID
51547
Accession Number
NP_057622
Molecular Weight
44898
Application Notes
SIRT7 antibody can be used for detection of SIRT7 by Western blot at 0.5 - 1 µg/mL.
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Storage Note
SIRT7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ASC11140 Datasheet
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