ZGPAT Antibody
Catalogue Number: ASC11410-ABG
ASC11410 Image
ASC11410 Image
ASC11410 Image
Western blot analysis of ZGPAT in SK-N-SH cell lysate with ZGPAT antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
ASC11410 Image
Immunofluorescence of ZGPAT in human brain cells with ZGPAT antibody at 20 µg/mL.
| Manufacturer: | Abcepta |
| Shelf Life: | 12 months |
| Molecular Weight: | 57359 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | |
| Application: | ELISA, IF, WB |
Description
Description: ZGPAT Antibody: The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.
Additional Text
Accession Number
NP_115916
Molecular Weight
57359
Gene ID
84619
Gene Name
ZGPAT
Uniprot ID
Q8N5A5
Application Notes
ZGPAT antibody can be used for detection of ZGPAT by Western blot at 1 µg/mL. Antibody can also be used for immunofluorescence starting at 20 µg/mL. For immunofluorescence start at 20 µg/mL.
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Storage Note
ZGPAT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ASC11410 Datasheet
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