SIK3 Antibody

Catalogue Number: ASC11411-ABG

Manufacturer:Abcepta
Shelf Life:12 months
Molecular Weight:144851
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Chicken
Clone:
Isotype: IgY
Immunogen:
Application: ELISA, IF, WB

Description

Description: SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.

Additional Text

Accession Number

NP_079440

Gene ID

23387

Gene Name

SIK3

Uniprot ID

Q9Y2K2

Application Notes

SIK3 antibody can be used for detection of SIK3 by Western blot at 1 µg/mL. Antibody can also be used for immunofluorescence starting at 20 µg/mL. For immunofluorescence start at 20 µg/mL.

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Storage Note

SIK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Molecular Weight

144851