APC Anti-Mouse CD86 (B7-2) (GL-1) Antibody
Catalogue Number: ATB10032-ABG
ATB10032 Image
ATB10032 Image
ATB10032 Image
C57Bl/6 splenocytes were unstimulated (left panel) or stimulated for 3 days with LPS (right panel) and stained with 0.06 ug APC Anti-Mouse CD86 (ATB10032) (solid line) or 0.06 ug APC Rat IgG2a isotype control (dashed line).
ATB10032 Image
C57Bl/6 splenocytes were stimulated for 3 days with LPS and then stained with 0.06 ug APC Anti-Mouse CD86 (GL-1) manufactured by Tonbo Biosciences (left panel) or eBioscience (right panel).
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | B7.2, B70, Ly-58|B7.2, B70, Ly-58, CD86 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | GL-1 (GL1) |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.
Additional Text
Gene Name
CD86
Gene ID
12524
Application Notes
This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
Uniprot ID
P42082
Antibody Clonality
Monoclonal
Storage Note
2-8°C protected from light
ATB10032 Datasheet
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