Catalogue Number: ATB10048-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | LPAM-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | mouse, rat |
| Clone: | DATK32 |
| Isotype: | IgG2a, kappa |
| Immunogen: |
Description: The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.
This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
Monoclonal
2-8°C protected from light