APC Anti-Mouse LPAM-1 (DATK32) Antibody

Catalogue Number: ATB10048-ABG

Manufacturer:Abcepta
Type:Monoclonal Primary Antibody - Conjugated
Alias:LPAM-1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: mouse, rat
Clone: DATK32
Isotype: IgG2a, kappa
Immunogen:

Description

Description: The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.

Additional Text

Application Notes

This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.

Antibody Clonality

Monoclonal

Storage Note

2-8°C protected from light