APC Anti-Mouse IL-4 (11B11) Antibody

Catalogue Number: ATB10055-ABG

Manufacturer:	Abcepta
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	IL4, Interleukin-4, BSF-1\|IL4, Interleukin-4, BSF-1, IL-4
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rat
Clone:	11B11
Isotype:	IgG1, kappa
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions. Please choose the appropriate format for each application.

Additional Text

Gene Name

IL4

Gene ID

16189

Application Notes

This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.

Uniprot ID

P07750

Antibody Clonality

Monoclonal

Storage Note

2-8°C protected from light

ATB10055 Datasheet

Price

£166.00

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