In Vivo Ready™ Anti-Mouse Ly-6G (Gr-1) (RB6-8C5) Antibody

Catalogue Number: ATB10155-ABG

Manufacturer:	Abcepta
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Gr1, Ly6G\|Lymphocyte antigen 6C1, Ly-6C1, Ly6c1
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	1 mg
Host name:	Rat
Clone:	RB6-8C5
Isotype:	IgG2b, kappa
Immunogen:
Application:	FC, IHC-P, IP, IHC-Fr, FA

Overview
Datasheets

Description

Description: The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200.

Additional Text

Application Notes

This purified format is guaranteed to be >90% pure as determined by SDS-PAGE analysis. Citations are provided as a convenience to you - please consult Materials and Methods sections for additional details about the use of any product in these publications.

Gene ID

17067

Gene Name

Ly6c1

Uniprot ID

P0CW02

Antibody Clonality

Monoclonal

Storage Note

2-8°C

ATB10155 Datasheet

Price

£323.00

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