PE-Cy7 Anti-Human CD25 (BC96) Antibody

Catalogue Number: ATB10243-ABG

Manufacturer:	Abcepta
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra, Tac\|Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	BC96
Isotype:	IgG1, kappa
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells.The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on - nduced - peripheral Tregs. This antibody is cross-reactive with CD25 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus.

Additional Text

Gene Name

IL2RA

Gene ID

3559

Uniprot ID

P01589

Application Notes

This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 uL per test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.

Antibody Clonality

Monoclonal

Storage Note

2-8°C protected from light

ATB10243 Datasheet

Price

£165.00

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