PE Anti-Mouse Foxp3 (MF23) Antibody
Catalogue Number: ATB10378-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Forkhead box P3, Scurfin, JM2|Forkhead box protein P3, Scurfin, Foxp3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | MF23 |
| Isotype: | IgG2b |
| Immunogen: | |
| Application: | FC |
Description
Description: The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Additional Text
Gene Name
FOXP3
Uniprot ID
Q99JB6
Gene ID
20371
Application Notes
This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. It is recommended to use the Transcription Factor Staining Buffer Kit (TNB-0607-KIT) for optimal staining results with this antibody.
Antibody Clonality
Monoclonal
Storage Note
2-8°C protected from light
ATB10378 Datasheet
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