redFluor™ 710 Anti-Human CD19 (HIB19) Antibody

Catalogue Number: ATB10408-ABG

Manufacturer:Abcepta
Type:Monoclonal Primary Antibody - Conjugated
Alias:B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19|Leu-12, B4
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: HIB19
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

Additional Text

Gene Name

CD19

Gene ID

930

Uniprot ID

P15391

Antibody Clonality

Monoclonal

Storage Note

2-8°C protected from light