Catalogue Number: ATB10433-ABG
| Manufacturer: | Abcepta |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Leukocyte Common Antigen, LCA, Ly-5, Hle-1|Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, T200, CD45, PTPRC, CD45 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 500 tests |
| Host name: | Mouse |
| Clone: | 2D1 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description: The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO. The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.
PTPRC
5788
P08575
Monoclonal
2-8°C protected from light