APC-Cyanine7 Anti-Human CD45RA Antibody (HI100)

Catalogue Number: ATB10460-ABG

Manufacturer:Abcepta
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: HI100
Isotype: IgG2b, kappa
Immunogen:
Application: FC

Description

Description: The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others. The HI100 antibody is widely used as a marker for human CD45RA expression on naive and activated T cells, B cells, and monocytes.

Additional Text

Gene ID

5788

Antibody Clonality

Monoclonal

Storage Note

2-8°C protected from light

Gene Name

PTPRC