B-Raf inhibitor 1

Catalogue Number: B1172-APE

Manufacturer:Apexbio
Molecular Formula:C26H19ClN8
Physical state:A solid
Type:Kinase Inhibitors
Shipping Condition:Blue Ice
Unit(s): 10 mg, 100 mg, 5 mg, 50 mg

Description

Description: B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.

Additional Text

Storage Note

Store at -20°C

Solubility

≥47.9 mg/mL in DMSO; insoluble in H2O; ≥5.88 mg/mL in EtOH with ultrasonic

Short Description

Potent and selective B-Raf inhibitor

Smile String

Cc(ccc1c2ccnc1Nc(cc1)ccc1Cl)c2Nc1ncccc1-c1ncnc2c1[nH]cn2

Price
£155.00


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