Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (MaxLight 490)
Catalogue Number: B2103-06-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 11C233 (L6/60) |
| Isotype: | IgG2a, kappa |
| Immunogen: | Recombinant protein corresponding to the S9-S10 segments of mouse Slo1. |
| Application: | ICC, WB, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Slo1 (Calcium-activated potassium channel subunit alpha-1) may not only be activated by membrane depolarization but may also be by an increase in cytosolic Ca2+. The concentration of cytosolic Mg2+ also activates this potassium channel. Found to play a part in the repolarization of the membrane potential due to the fact that it diminishes the excitatory voltage in the cell.
Additional Text
Gene Name
KCNMA1
Accession Number
NP_034740
Uniprot ID
Q08460
Specificity
Recognizes S9-S10 segments of Slo1. Species Crossreactivity: rat Species Sequence Homology: mouse
Purification
Protein G purified
Gene ID
16531
Antibody Clonality
Monoclonal
B2103-06-ML490 Datasheet
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