Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT) (MaxLight 650)

Catalogue Number: B2674-75A-ML650-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	brachyury protein\|protein T\|SAVA\|T\|T brachyury transcription factor\|T, brachyury homolog\|T-box transcription factor T\|TFT
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	3E4.2
Isotype:	IgG1, kappa
Immunogen:	Synthetic human brachyury peptide, aa224-435. Epitope: C-terminus.
Application:	WB

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The Brachyury protein is a T-box transcription factor that is one of the earliest indicators of mesoderm formation during embryonic development. As the brachyury protein family is essential for the formation of the posterior body in all vertebrates, Brachyury has been shown to be expressed during gastrula and neurula stages, as well as in the developing notochord. Consequently, when mutations occur within the brachyury gene, severe vertebral malformations have been found to occur, as a direct result. In addition, current findings also indicate that the dysregulation of brachyury may also be linked to the formation of chordomas, which are malignant tumors that develop along the spine.

Additional Text

Accession Number

NM_003181.2

Gene ID

6862

Specificity

Recognizes human brachyury.

Purification

Protein G purified

Uniprot ID

O15178

Gene Name

TBXT

Antibody Clonality

Monoclonal

B2674-75A-ML650 Datasheet

Price

£979.00

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