Bu-1b (FITC)

Catalogue Number: B2788-55A-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with FITC.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Mouse
Clone: 5-11G2
Isotype: IgG1, kappa
Immunogen: Bursal cells from 2- to 5-week-old CHA (Bu-1b) strain chickens
Application: FC, IP, IHC

Description

Description: Chicken Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes, but not on granulocytes, erythrocytes or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion.

Additional Text

Caution

FOR RESEARCH USE ONLY

Specificity

Recognizes chicken Bu-1b alloantigen, Mr 70kD. Does not react with cells from CHA and H.B15Ab strains by immunofluorescence.

Purification

Purified

Antibody Clonality

Monoclonal