Catalogue Number: B671-LET
| Manufacturer: | Leinco Technologies, Inc |
| Shelf Life: | 6 months |
| Type: | Biological Buffers |
| Shipping Condition: | RT |
| Unit(s): | 100 ml |
| Application: | IHC |
Description: The ADAPT-3D™ Decolorization Buffer is a crucial component of the ADAPT-3D (Accelerated Deep Adaptable Processing of Tissue for 3-Dimensional Fluorescence Tissue Imaging) method. In 3D tissue imaging, a significant challenge is the presence of light-interfering substances within the tissue, such as pigments and lipids, which can scatter light and hinder deep penetration and clear visualization. The Decolorization Buffer specifically addresses this by working to remove these light-absorbing and scattering molecules from the tissue. This process, often combined with delipidation (removal of lipids), makes the tissue more transparent and allows for superior light penetration during fluorescence microscopy. By effectively "decoloring" the tissue, the buffer enhances the signal-to-noise ratio and improves the overall quality and depth of 3D imaging, leading to clearer and more accurate representations of cellular structures and organization. This step is vital for achieving the rapid processing and high-quality results that ADAPT-3D aims to deliver.
Store the buffer at room temperature in a dry environment, ensuring it is protected from moisture and temperature fluctuations. Do not freeze the product; when stored as directed, it maintains full potency and stability for up to six months.