Catalogue Number: B8175-APE
Manufacturer: | Apexbio |
Molecular Weight: | 817.4 g/mol (free acid) |
Molecular Formula: | C22H32N10O18P3 (free acid) |
Type: | Biochemicals |
Alias: | Anti Reverse Cap Analog, 3'-O-Me-m7G(5')ppp(5')G |
Shipping Condition: | Blue Ice |
Storage Condition: | -20°C/-70°C |
Unit(s): | 10 ul (100 mM), 100 ul (100 mM), 50 ul (100 mM) |
Description: A critical step in mRNA processing is the addition of a 5' cap structure, a 5'-5' triphosphate linkage between the 5' initiating terminal of the RNA and a guanosine nucleotide. The cap is then methylated enzymatically at the N-7 position of the guanosine to form a mature mCAP.
Anti Reverse Cap Analog (ARCA) used to forming Cap 0 structure, 3'-O-Me-m7G(5')ppp(5')G
OC1C(COP([O-])(OP([O-])(OP([O-])(OCC2OC(N3C=[N+](C)C4=C3N=C(N)NC4=O)C(O)C2OC)=O)=O)=O)OC(N5C=NC6=C5N=C(N)NC6=O)C1O