FITC-Labeled Human B7-H3 (4Ig) /B7-H3b Protein (BH7-HM23BF)

Catalogue Number: BH7-HM23BF-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 73.4 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Protein - Conjugated
Alias:B7-H3; CD276; PSEC0249; 4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig-B7-H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Additional Text

Protein Tag

hFC Tag

Uniprot ID

Q5ZPR3-1

Short Description

Recombinant FITC-Labeled Human B7-H3 (4Ig) /B7-H3b Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Gly27-Thr461.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£707.00


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