Catalogue Number: BP9685C-ABG
Manufacturer: | Abcepta |
Type: | Blocking Peptides |
Alias: | Toll-like receptor 4, hToll, CD284, TLR4 |
Shipping Condition: | Blue Ice |
Unit(s): | 500 ug |
Description: TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
TLR4
O00206
7099
Synthetic peptide
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.