Cytochrome C Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated

Catalogue Number: BS-0013R-A594-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Preservative:0.09% Sodium azide
Type:Polyclonal Primary Antibody - Conjugated
Alias:CYC; HCS; THC4; Cytochrome c; CYCS
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Cytochrome C
Application: ICC

Description

Description: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Additional Text

Concentration

1ug/ul

Applications with dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Excitation/ Emission Wavelengths

590nm/617nm

Modification

Unmodified

Synonym

CYC; HCS; THC4; Cytochrome c; CYCS