PKM2 Polyclonal Antibody, Cy5.5 Conjugated
Catalogue Number: BS-0101R-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse Pyruvate kinase PKM |
| Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Additional Text
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Gene ID
5313; 5315
Gene Name
PKLR, PKM
Modification
Unmodified
Specificity
PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-3; Pyruvate kinase PKM; Cytosolic thyroid hormone-binding protein; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Tumor M2-PK; p58; PKM; PK2; Pyruvate kinase PKLR; Pyruvate kinase 1; R-type/L-type pyruvate kinase; Red cell/liver pyruvate kinase.
Uniprot ID
P14618, P30613
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
bs-0101R-Cy5.5 Datasheet
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