Glucocorticoid receptor Antibody, Cy7 Conjugated
Catalogue Number: BS-0252R-CY7-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | GR; GCR; GRL; GCCR; GCRST; Glucocorticoid receptor; Nuclear receptor subfamily 3 group C member 1; NR3C1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human Glucocorticoid receptor |
| Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.
Additional Text
Gene ID
2908
Gene Name
NR3C1
Uniprot ID
P04150
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
743nm/767nm
bs-0252R-Cy7 Datasheet
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