C5a anaphylatoxin Polyclonal Antibody, Cy7 Conjugated
Catalogue Number: BS-0324R-CY7-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | C5; He; C5a; Complement C5; Hemolytic complement; Hc |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse C5a (725-770aa) |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Additional Text
Gene ID
15139
Uniprot ID
P06684
Purification
Protein A purified
Concentration
1 ug/ul
Gene Name
Hc
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
743nm/767nm
bs-0324R-Cy7 Datasheet
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