CRHR1 Polyclonal Antibody, Cy5.5 Conjugated
Catalogue Number: BS-10248R-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | Corticotropin-releasing factor receptor 1; CRHR1; CRF-R-1; CRF-R1; CRFR-1; CRFR |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human CRHR1 |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
Additional Text
Uniprot ID
P34998
Purification
Protein A purified
Gene ID
104909134; 1394
Concentration
1 ug/ul
Gene Name
CRHR1, LINC02210-CRHR1
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
675nm/694nm
BS-10248R-CY5.5 Datasheet
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