Catalogue Number: BS-10287R-FITC-BSS
Manufacturer: | Bioss Inc |
Type: | Polyclonal Primary Antibody - Conjugated |
Alias: | GADD34; Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog; PPP1R15A |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from human GADD34 |
Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
PPP1R15A
O75807
23645
Protein A purified
1 ug/ul
Polyclonal
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.