C4b-A Polyclonal Antibody, AbBy Fluor-350 Conjugated

Catalogue Number: BS-10452R-BF350-BSS

Manufacturer:	Bioss Inc
Type:	Polyclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	KLH conjugated synthetic peptide derived from human C4A
Application:	ICC, IF, IHC-P, IHC-Fr

Overview
Datasheets

Description

Description: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

Additional Text

Uniprot ID

P0C0L4

Purification

Protein A purified

Gene ID

720; 721

Concentration

1 ug/ul

Gene Name

C4A, C4B

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

C4b-A; complement C4-A proprotein; Acidic complement C4; Basic complement C4; CH; Chido blood group; Complement component 4A; Complement component 4B; RG; Rodgers blood group; CO4A_HUMAN; CO4B_HUMAN; C4A; C4; C4A2; C4A3; C4A4; C4A6; C4AD; C4S; CO4; CPAMD2; RG.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

346nm/442nm

BS-10452R-BF350 Datasheet

Price

£379.00

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