DYNC1I1 Polyclonal Antibody, PerCP-Cy5.5 Conjugated

Catalogue Number: BS-10470R-PERCP-CY5.5-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human DYNC1I1
Application: FC, ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

Additional Text

Gene Name

DYNC1I1

Gene ID

1780

Uniprot ID

O14576

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

dynein, cytoplasmic, intermediate polypeptide 1; cytoplasmic dynein 1 intermediate chain 1; DH IC-1; dynein intermediate chain 1, cytosolic; cytoplasmic dynein intermediate chain 1; DC1I1_HUMAN; DYNC1I1; DNCI1; DNCIC1; Dynein cytoplasmic intermediate polypeptide 1.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

482nm/694nm