Recombinant human NT-proBNP protein, N-His
Catalogue Number: BS-10879P-BSS
| Manufacturer: | Bioss Inc |
| Type: | Other Recombinant Protein |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Storage Condition: | -70°C |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76mino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Additional Text
Gene Name
NPPB
Gene ID
4879
Uniprot ID
P16860
Protein Tag
HIS Tag
Storage Note
The product should be stored at -70°C or -20°C.
Short Description
Recombinant human NT-proBNP protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 27-102/134.
Endotoxin
Not Tested
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