Recombinant human GAPDH protein, C-His
Catalogue Number: BS-10900P-BSS
| Manufacturer: | Bioss Inc |
| Type: | Other Enzymes |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Storage Condition: | -70°C |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 38kDa subunits.
Additional Text
Gene Name
GAPDH
Gene ID
2597
Uniprot ID
P04406
Protein Tag
HIS Tag
Storage Note
The product should be stored at -70°C or -20°C.
Short Description
Recombinant human GAPDH protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 2-335/335.
Endotoxin
Not Tested
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